Mutation frequency declines during spermatogenesis in young mice but increases in old mice

Five percent of live-born human offspring will have a genetic disorder. Of these, 20% are because of germ-line de novo mutations. Several genetic diseases, such as neurofibromatosis and Duchenne muscular dystrophy, are associated with a high percentage of de novo germ-line mutations. Until recently,...

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Detaylı Bibliyografya
Asıl Yazarlar: Walter, Christi A., Intano, Gabriel W., McCarrey, John R., McMahan, C. Alex, Walter, Ronald B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC21453/
https://ncbi.nlm.nih.gov/pubmed/9707592
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