Base Excision Repair Is Limited by Different Proteins in Male Germ Cell Nuclear Extracts Prepared from Young and Old Mice

The combined observations of elevated DNA repair gene expression, high uracil-DNA glycosylase-initiated base excision repair, and a low spontaneous mutant frequency for a lacI transgene in spermatogenic cells from young mice suggest that base excision repair activity is high in spermatogenic cell ty...

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Detalhes bibliográficos
Main Authors: Intano, Gabriel W., McMahan, C. Alex, McCarrey, John R., Walter, Ronald B., McKenna, Allison E., Matsumoto, Yoshihiro, MacInnes, Mark A., Chen, David J., Walter, Christi A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133670/
https://ncbi.nlm.nih.gov/pubmed/11884623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2410-2418.2002
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