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Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.

Beta-lactamases are involved in bacterial resistance. Members of the metallo-enzyme class are now found in many pathogenic bacteria and are becoming thus of major clinical importance. Despite the availability of Zn-beta-lactamase X-ray structures their mechanism of action is still unclear. One puzzl...

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Main Authors: Chantalat, L., Duée, E., Galleni, M., Frère, J. M., Dideberg, O.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144673/
https://ncbi.nlm.nih.gov/pubmed/10933508
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