Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA.

One alternative method for drug delivery involves the use of siderophore-antibiotic conjugates. These compounds represent a specific means by which potent antimicrobial agents, covalently linked to iron-chelating siderophores, can be actively transported across the outer membrane of gram-negative ba...

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Bibliografiska uppgifter
Huvudupphovsmän: Ferguson, A. D., Braun, V., Fiedler, H. P., Coulton, J. W., Diederichs, K., Welte, W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2000
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144648/
https://ncbi.nlm.nih.gov/pubmed/10850805
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