Backbone dynamics measurements on leukemia inhibitory factor, a rigid four-helical bundle cytokine.

The backbone dynamics of the four-helical bundle cytokine leukemia inhibitory factor (LIF) have been investigated using 15N NMR relaxation and amide proton exchange measurements on a murine-human chimera, MH35-LIF. For rapid backbone motions (on a time scale of 10 ps to 100 ns), as probed by 15N rel...

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Autori principali: Yao, S., Smith, D. K., Hinds, M. G., Zhang, J. G., Nicola, N. A., Norton, R. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144613/
https://ncbi.nlm.nih.gov/pubmed/10794409
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