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DNA inhibits catalysis by the carboxyltransferase subunit of acetyl-CoA carboxylase: Implications for active site communication

Acetyl-CoA carboxylase (ACC) catalyzes the first committed step in the synthesis of long-chain fatty acids. The crystal structure of the Escherichia coli carboxyltransferase component of ACC revealed an α(2)β(2) subunit composition with two active sites and, most importantly, a unique zinc domain in...

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Autors principals: Benson, Brian K., Meades, Glen, Grove, Anne, Waldrop, Grover L.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144591/
https://ncbi.nlm.nih.gov/pubmed/18156466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073186408
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