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DNA inhibits catalysis by the carboxyltransferase subunit of acetyl-CoA carboxylase: Implications for active site communication
Acetyl-CoA carboxylase (ACC) catalyzes the first committed step in the synthesis of long-chain fatty acids. The crystal structure of the Escherichia coli carboxyltransferase component of ACC revealed an α(2)β(2) subunit composition with two active sites and, most importantly, a unique zinc domain in...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2144591/ https://ncbi.nlm.nih.gov/pubmed/18156466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073186408 |
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