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A new approach to the design of uniquely folded thermally stable proteins.

A new computer program (CORE) is described that predicts core hydrophobic sequences of predetermined target protein structures. A novel scoring function is employed, which for the first time incorporates parameters directly correlated to free energies of unfolding (deltaGu), melting temperatures (Tm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jiang, X., Farid, H., Pistor, E., Farid, R. S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144549/
https://ncbi.nlm.nih.gov/pubmed/10716193
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