Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel.

HpTX2 is a toxin from the venom of Heteropoda venatoria spider that has been demonstrated to bind on Kv4.2 potassium channel. We have determined the solution structure of recombinant HpTX2 by use of conventional two-dimensional NMR techniques followed by distance-geometry and molecular dynamics. The...

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Main Authors: Bernard, C., Legros, C., Ferrat, G., Bischoff, U., Marquardt, A., Pongs, O., Darbon, H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144494/
https://ncbi.nlm.nih.gov/pubmed/11152117
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