Laddar...
Change in oligomerization specificity of the p53 tetramerization domain by hydrophobic amino acid substitutions.
The tumor suppressor function of the wild-type p53 protein is transdominantly inhibited by tumor-derived mutant p53 proteins. Such transdominant inhibition limits the prospects for gene therapy approaches that aim to introduce wild-type p53 into cancer cells. The molecular mechanism for transdominan...
Sparad:
| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
1999
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2144399/ https://ncbi.nlm.nih.gov/pubmed/10493578 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|