Oligomerization of the tetramerization domain of p53 probed by two- and three-color single-molecule FRET

We describe a method that combines two- and three-color single-molecule FRET spectroscopy with 2D FRET efficiency–lifetime analysis to probe the oligomerization process of intrinsically disordered proteins. This method is applied to the oligomerization of the tetramerization domain (TD) of the tumor...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Chung, Hoi Sung, Meng, Fanjie, Kim, Jae-Yeol, McHale, Kevin, Gopich, Irina V., Louis, John M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565410/
https://ncbi.nlm.nih.gov/pubmed/28760960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700357114
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