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X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs.

The pokeweed antiviral protein (PAP) belongs to a family of ribosome-inactivating proteins (RIP), which depurinate ribosomal RNA through their site-specific N-glycosidase activity. We report low temperature, three-dimensional structures of PAP co-crystallized with adenyl-guanosine (ApG) and adenyl-c...

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Bibliografski detalji
Glavni autori: Kurinov, I. V., Myers, D. E., Irvin, J. D., Uckun, F. M.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144398/
https://ncbi.nlm.nih.gov/pubmed/10493577
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