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Variants of ribonuclease inhibitor that resist oxidation.

Human ribonuclease inhibitor (hRI) is a cytosolic protein that protects cells from the adventitious invasion of pancreatic-type ribonucleases. hRI has 32 cysteine residues. The oxidation of these cysteine residues to form disulfide bonds is a rapid, cooperative process that inactivates hRI. The most...

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Bibliografische gegevens
Hoofdauteurs: Kim, B. M., Schultz, L. W., Raines, R. T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144251/
https://ncbi.nlm.nih.gov/pubmed/10048337
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