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Molecular dynamics investigation of the effect of an antiviral compound on human rhinovirus.

The factors that influence the enhanced stability observed experimentally of human rhinovirus 14 (HRV14) upon binding a hydrophobic antiviral drug have been investigated by molecular dynamics. Simulations centered about the HRV14 drug-binding pocket allow the reliable assessment of differences in ca...

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Detalles Bibliográficos
Autores principales: Phelps, D. K., Post, C. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144186/
https://ncbi.nlm.nih.gov/pubmed/10595531
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