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A near-native state on the slow refolding pathway of hen lysozyme.

The refolding of four disulfide lysozyme (at pH 5.2, 20 degrees C) involves parallel pathways, which have been proposed to merge at a near-native state. This species contains stable structure in the alpha- and beta-domains but lacks a functional active site. Although previous experiments have demons...

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Main Authors: Kulkarni, S. K., Ashcroft, A. E., Carey, M., Masselos, D., Robinson, C. V., Radford, S. E.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144118/
https://ncbi.nlm.nih.gov/pubmed/10210181
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