Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.

Two synthetic analogues of murine epidermal growth factor, [Abu6, 20] mEGF4-48 (where Abu denotes amino-butyric acid) and [G1, M3, K21, H40] mEGF1-48, have been investigated by NMR spectroscopy. [Abu6, 20] mEGF4-48 was designed to determine the contribution of the 6-20 disulfide bridge to the struct...

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Detalhes bibliográficos
Main Authors: Barnham, K. J., Torres, A. M., Alewood, D., Alewood, P. F., Domagala, T., Nice, E. C., Norton, R. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144085/
https://ncbi.nlm.nih.gov/pubmed/10082370
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