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MgATP binding to the nucleotide-binding domains of the eukaryotic cytoplasmic chaperonin induces conformational changes in the putative substrate-binding domains.

The eukaryotic cytosolic chaperonins are large heterooligomeric complexes with a cylindrical shape, resembling that of the homooligomeric bacterial counterpart, GroEL. In analogy to GroEL, changes in shape of the cytosolic chaperonin have been detected in the presence of MgATP using electron microsc...

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Bibliografische gegevens
Hoofdauteurs: Szpikowska, B. K., Swiderek, K. M., Sherman, M. A., Mas, M. T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144052/
https://ncbi.nlm.nih.gov/pubmed/9684884
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