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Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor.
Tissue factor (TF), a member of the cytokine receptor superfamily, is the obligate cofactor of coagulation factor VIIa (FVIIa), and has a pivotal role in initiating the extrinsic pathway of blood coagulation through formation of the TF x FVIIa complex. The crystal structure of the extracellular port...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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Cold Spring Harbor Laboratory Press
1998
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2144006/ https://ncbi.nlm.nih.gov/pubmed/9605315 |
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