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Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A.

The Tyr92-Pro93 peptide group of bovine pancreatic ribonuclease A (RNase A) exists in the cis conformation in the native state. From unfolding/refolding kinetic studies of the disulfide-intact wild-type protein and of a variant in which Pro93 had been replaced by Ala, it had been suggested that the...

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Detalhes bibliográficos
Main Authors: Pearson, M. A., Karplus, P. A., Dodge, R. W., Laity, J. H., Scheraga, H. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143996/
https://ncbi.nlm.nih.gov/pubmed/9605332
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