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Surface salt bridges stabilize the GCN4 leucine zipper.

We present a study of the role of salt bridges in stabilizing a simplified tertiary structural motif, the coiled-coil. Changes in GCN4 sequence have been engineered that introduce trial patterns of single and multiple salt bridges at solvent exposed sites. At the same sites, a set of alanine mutants...

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Détails bibliographiques
Auteurs principaux: Spek, E. J., Bui, A. H., Lu, M., Kallenbach, N. R.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143877/
https://ncbi.nlm.nih.gov/pubmed/9828010
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