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Electrostatic Contributions to the Stability of the GCN4 Leucine Zipper Structure
Ion pairs are ubiquitous in X-ray structures of coiled coils, and mutagenesis of charged residues can result in large stability losses. By contrast, pK(a) values determined by NMR in solution often predict only small contributions to stability from charge interactions. To help reconcile these result...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2105789/ https://ncbi.nlm.nih.gov/pubmed/17920624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.09.007 |
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