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Prime region subsite specificity characterization of human cathepsin D: the dominant role of position 128.

In order to contribute to our understanding of cathepsin D (CatD) active site specificity, two series of chromogenic octapeptides with systematic substitutions in positions P2' and P3' were synthesized. This panel was characterized with native human liver cathepsin D (nHuCatD) and yielded...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beyer, B. M., Dunn, B. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143827/
https://ncbi.nlm.nih.gov/pubmed/9514263
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