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Coupling backbone flexibility and amino acid sequence selection in protein design.

Using a protein design algorithm that considers side-chain packing quantitatively, the effect of explicit backbone motion on the selection of amino acids in protein design was assessed in the core of the streptococcal protein G beta 1 domain (G beta 1). Concerted backbone motion was introduced by va...

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Bibliografiske detaljer
Main Authors: Su, A., Mayo, S. L.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143777/
https://ncbi.nlm.nih.gov/pubmed/9260282
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