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Binding of monoclonal antibody 4B1 to homologs of the lactose permease of Escherichia coli.

The conformationally sensitive epitope for monoclonal antibody (mAb) 4B1, which uncouples lactose from H+ translocation in the lactose permease of Escherichia coli, is localized in the periplasmic loop between helices VII and VIII (loop VII/VIII) on one face of a short helical segment (Sun J, et al....

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Bibliographic Details
Main Authors: Sun, J., Frillingos, S., Kaback, H. R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143751/
https://ncbi.nlm.nih.gov/pubmed/9232651
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