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Characterization of the receptor binding determinants of granulocyte colony stimulating factor.
We performed a series of experiments using alanine-scanning mutagenesis to locate side chains within human granulocyte colony-stimulating factor (G-CSF) that are involved in human G-CSF receptor binding. We constructed a panel of 28 alanine mutants that examined all surface exposed residues on helic...
में बचाया:
मुख्य लेखकों: | , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Cold Spring Harbor Laboratory Press
1997
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2143731/ https://ncbi.nlm.nih.gov/pubmed/9194183 |
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