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Intrachain disulfide bond in the core hinge region of human IgG4.

IgG is a tetrameric protein composed of two copies each of the light and heavy chains. The four-chain structure is maintained by strong noncovalent interactions between the amino-terminal half of pairs of heavy-light chains and between the carboxyl-terminal regions of the two heavy chains. In additi...

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Bibliographische Detailangaben
Hauptverfasser: Bloom, J. W., Madanat, M. S., Marriott, D., Wong, T., Chan, S. Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143633/
https://ncbi.nlm.nih.gov/pubmed/9041643
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