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Demonstration of protein-protein interaction specificity by NMR chemical shift mapping.
Chemical shift mapping is becoming a popular method for studying protein-protein interactions in solution. The technique is used to identify putative sites of interaction on a protein surface by detecting chemical shift perturbations in simple (1H, 15N)-HSQC NMR spectra of a uniformly labeled protei...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
1997
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2143627/ https://ncbi.nlm.nih.gov/pubmed/9416611 |
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