A carregar...
Crystal structures of a marginally active thymidylate synthase mutant, Arg 126-->Glu.
Thymidylate synthase (TS) is a long-standing target for anticancer drugs and is of interest for its rich mechanistic features. The enzyme catalyzes the conversion of dUMP to dTMP using the co-enzyme methylenetetrahydrofolate, and is perhaps the best studied of enzymes that catalyze carbon-carbon bon...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
1997
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2143623/ https://ncbi.nlm.nih.gov/pubmed/9416600 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|