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Molecular mechanics calculations on Rous sarcoma virus protease with peptide substrates.

Molecular models of Rous sarcoma virus (RSV) protease and 20 peptide substrates with single amino acid substitutions at positions from P4 to P3', where the scissile bond is between P1 and P1'. were built and compared with kinetic measurements. The unsubstituted peptide substrate. Pro-Ala-V...

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Autores principales: Weber, I. T., Harrison, R. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143590/
https://ncbi.nlm.nih.gov/pubmed/9385639
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