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Importance of the N Terminus of Rous Sarcoma Virus Protease for Structure and Enzymatic Function

All retrovirus proteases (PRs) are homodimers, and dimerization is essential for enzymatic function. The dimer is held together largely by a short four-stranded antiparallel beta sheet composed of the four or five N-terminal amino acid residues and a similar stretch of residues from the C terminus....

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Detalhes bibliográficos
Main Authors: Schatz, Gisela W., Reinking, Jeffrey, Zippin, Jonathan, Nicholson, Linda K., Vogt, Volker M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114231/
https://ncbi.nlm.nih.gov/pubmed/11312348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4761-4770.2001
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