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Importance of the N Terminus of Rous Sarcoma Virus Protease for Structure and Enzymatic Function

All retrovirus proteases (PRs) are homodimers, and dimerization is essential for enzymatic function. The dimer is held together largely by a short four-stranded antiparallel beta sheet composed of the four or five N-terminal amino acid residues and a similar stretch of residues from the C terminus....

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Autori principali: Schatz, Gisela W., Reinking, Jeffrey, Zippin, Jonathan, Nicholson, Linda K., Vogt, Volker M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114231/
https://ncbi.nlm.nih.gov/pubmed/11312348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4761-4770.2001
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