A fragment of staphylococcal nuclease with an OB-fold structure shows hydrogen-exchange protection factors in the range reported for "molten globules".

Hydrogen-exchange rates for an OB-fold subdomain fragment of staphylococcal nuclease have been measured at pH 4.7 and 4 degrees C, conditions close to the minimum of acid/base catalyzed exchange. The strongest protection from solvent exchange is observed for residues from a five-stranded beta-barrel...

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Bibliographic Details
Main Authors: Alexandrescu, A. T., Dames, S. A., Wiltscheck, R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143544/
https://ncbi.nlm.nih.gov/pubmed/8880922
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