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Partially Folded States of Staphylococcal Nuclease Highlight the Conserved Structural Hierarchy of OB-Fold Proteins

We have been interested in whether three proteins that share a five-stranded β-barrel “OB-fold” structural motif but no detectable sequence homology fold by similar mechanisms. Here we describe native-state hydrogen exchange experiments as a function of urea for SN (staphylococcal nuclease), a prote...

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Main Authors: Watson, Emma, Matousek, William M., Irimies, Evelyn L., Alexandrescu, Andrei T.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128864/
https://ncbi.nlm.nih.gov/pubmed/17661445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700532j
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