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Coupling between trans/cis proline isomerization and protein stability in staphylococcal nuclease.

The nucleases A produced by two strains of Staphylococcus aureus, which have different stabilities, differ only in the identity of the single amino acid at residue 124. The nuclease from the Foggi strain of S. aureus (by convention nuclease WT), which contains His124, is 1.9 kcal.mol-1 less stable (...

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Hlavní autoři: Truckses, D. M., Somoza, J. R., Prehoda, K. E., Miller, S. C., Markley, J. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143535/
https://ncbi.nlm.nih.gov/pubmed/8880915
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