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3-Hydroxy-3-methylglutaryl-coenzyme A reductase of Haloferax volcanii: role of histidine 398 and attenuation of activity by introduction of negative charge at position 404.

Mutant 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductases of the halophilic archaeon Haloferax volcanii were constructed to test the proposed mechanism that phosphorylation downregulates the activity of higher eukarya HMG-CoA reductases via charge-charge interaction with the active site hist...

詳細記述

保存先:
書誌詳細
主要な著者: Bischoff, K. M., Rodwell, V. W.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143503/
https://ncbi.nlm.nih.gov/pubmed/9007988
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