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Flexibility of DNA binding domain of trp repressor required for recognition of different operator sequences.

Trp repressor (25 kDa) is a regulatory protein that controls transcription initiation in the tryptophan biosynthetic operon and at least four other operons in Escherichia coli. An alanine to valine mutation (AV77) in the DNA binding domain is known to increase repressor activity at the trp operator...

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Bibliografische gegevens
Hoofdauteurs: Gryk, M. R., Jardetzky, O., Klig, L. S., Yanofsky, C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143432/
https://ncbi.nlm.nih.gov/pubmed/8762153
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