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Flexibility of DNA binding domain of trp repressor required for recognition of different operator sequences.

Trp repressor (25 kDa) is a regulatory protein that controls transcription initiation in the tryptophan biosynthetic operon and at least four other operons in Escherichia coli. An alanine to valine mutation (AV77) in the DNA binding domain is known to increase repressor activity at the trp operator...

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Hlavní autoři: Gryk, M. R., Jardetzky, O., Klig, L. S., Yanofsky, C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143432/
https://ncbi.nlm.nih.gov/pubmed/8762153
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