Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1.

Several members of the ets gene family of transcription factors show negative regulation of DNA binding by intramolecular interactions. A structural mechanism for this auto-inhibition is investigated using a 161-residue N-terminal deletion mutant of murine Ets-1, Ets-1 delta N280. This protein shows...

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Autors principals: Skalicky, J. J., Donaldson, L. W., Petersen, J. M., Graves, B. J., McIntosh, L. P.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143348/
https://ncbi.nlm.nih.gov/pubmed/8745408
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