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Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase.

The three-dimensional X-ray structure of a complex of the potent neuraminidase inhibitor 4-guanidino-Neu5Ac2en and influenza virus neuraminidase (Subtype N9) has been obtained utilizing diffraction data to 1.8 A resolution. The interactions of the inhibitor, solvent water molecules, and the active s...

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Autors principals: Varghese, J. N., Epa, V. C., Colman, P. M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143140/
https://ncbi.nlm.nih.gov/pubmed/7549872
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