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Primary structure and functional characterization of rat C5a: an anaphylatoxin with unusually high potency.

The anaphylatoxin C5a is a pro-inflammatory factor generated from C5 during complement activation. C5a derived from rat C5 exhibits significantly greater potency compared to C5a from other species. Rat C5a was 25-fold more potent than human C5a for eliciting spasmogenic contraction of guinea pig ile...

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Bibliografske podrobnosti
Main Authors: Cui, L., Carney, D. F., Hugli, T. E.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142913/
https://ncbi.nlm.nih.gov/pubmed/7987212
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