Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant

All parasitic protozoa studied to date are incapable of purine biosynthesis and must therefore salvage purine nucleobases or nucleosides from their hosts. This salvage process is initiated by purine transporters on the parasite cell surface. We have used a mutant line (TUBA5) of Leishmania donovani...

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Hauptverfasser: Vasudevan, Gayatri, Carter, Nicola S., Drew, Mark E., Beverley, Stephen M., Sanchez, Marco A., Seyfang, Andreas, Ullman, Buddy, Landfear, Scott M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21429/
https://ncbi.nlm.nih.gov/pubmed/9707568
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