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Characteristics of a de novo designed protein.

A series of 204 amino acid proteins intended to form TIM (triose phosphate isomerase) barrel structures were designed de novo. Each protein was synthesized by expression of the synthetic gene as a fusion protein with a portion of human growth hormone in an Escherichia coli host. After BrCN treatment...

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Autors principals: Tanaka, T., Kimura, H., Hayashi, M., Fujiyoshi, Y., Fukuhara, K., Nakamura, H.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142704/
https://ncbi.nlm.nih.gov/pubmed/8019413
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