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Role of the C-terminus in the activity, conformation, and stability of interleukin-6.

Two murine interleukin-6 (mIL-6) variants were constructed using the polymerase chain reaction (PCR), one lacking the last five residues (183-187) at the C-terminus (pMC5) and another with the last five residues of mIL-6 substituted by the corresponding residues of human IL-6 (pMC5H). The growth sti...

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Autors principals: Ward, L. D., Hammacher, A., Zhang, J. G., Weinstock, J., Yasukawa, K., Morton, C. J., Norton, R. S., Simpson, R. J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142456/
https://ncbi.nlm.nih.gov/pubmed/8401231
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