Human immunodeficiency virus type-1 reverse transcriptase and ribonuclease H as substrates of the viral protease.

A study has been made of the susceptibility of recombinant constructs of reverse transcriptase (RT) and ribonuclease H (RNase H) from human immunodeficiency virus type 1 (HIV-1) to digestion by the HIV-1 protease. At neutral pH, the protease attacks a single peptide bond, Phe440-Tyr441, in one of th...

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Bibliografiska uppgifter
Huvudupphovsmän: Tomasselli, A. G., Sarcich, J. L., Barrett, L. J., Reardon, I. M., Howe, W. J., Evans, D. B., Sharma, S. K., Heinrikson, R. L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 1993
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142316/
https://ncbi.nlm.nih.gov/pubmed/7507754
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