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Modeling alpha-helical transmembrane domains: the calculation and use of substitution tables for lipid-facing residues.

Amino acid substitution tables are calculated for residues in membrane proteins where the side chain is accessible to the lipid. The analysis is based upon the knowledge of the three-dimensional structures of two homologous bacterial photosynthetic reaction centers and alignments of their sequences...

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Detalhes bibliográficos
Main Authors: Donnelly, D., Overington, J. P., Ruffle, S. V., Nugent, J. H., Blundell, T. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142307/
https://ncbi.nlm.nih.gov/pubmed/8443590
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