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Design of a functional calcium channel protein: inferences about an ion channel-forming motif derived from the primary structure of voltage-gated calcium channels.

To identify sequence-specific motifs associated with the formation of an ionic pore, we systematically evaluated the channel-forming activity of synthetic peptides with sequence of predicted transmembrane segments of the voltage-gated calcium channel. The amino acid sequence of voltage-gated, dihydr...

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Detalles Bibliográficos
Autores principales: Grove, A., Tomich, J. M., Iwamoto, T., Montal, M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142287/
https://ncbi.nlm.nih.gov/pubmed/7505682
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