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NMR analysis of regioselectivity in dephosphorylation of a triphosphotyrosyl dodecapeptide autophosphorylation site of the insulin receptor by a catalytic fragment of LAR phosphotyrosine phosphatase.

An autophosphorylation site in the activated insulin receptor tyrosine kinase domain has three tyrosines phosphorylated when fully activated. To begin to examine recognition of triphosphotyrosyl sites by protein tyrosine phosphatases in possible control of signal transduction a triphosphotyrosyl dod...

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Библиографические подробности
Главные авторы: Lee, J. P., Cho, H., Bannwarth, W., Kitas, E. A., Walsh, C. T.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 1992
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142094/
https://ncbi.nlm.nih.gov/pubmed/1303753
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