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Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway and its Potential for Therapeutic Intervention in Malignancy and Ischemia

Hypoxia-Inducible Factor (HIF)-1 is a dimeric protein complex that plays an integral role in the body's response to low oxygen concentrations, or hypoxia. HIF-1 is among the primary genes involved in the homeostatic process, which can increase vascularization in hypoxic areas such as localized...

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Hlavní autoři: Ziello, Jennifer E., Jovin, Ion S., Huang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Yale Journal of Biology and Medicine 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140184/
https://ncbi.nlm.nih.gov/pubmed/18160990
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