Fusion of Lysosomes with Late Endosomes Produces a Hybrid Organelle of Intermediate Density and Is NSF Dependent

Using a cell-free content mixing assay containing rat liver endosomes and lysosomes in the presence of pig brain cytosol, we demonstrated that after incubation at 37°C, late endosome–lysosome hybrid organelles were formed, which could be isolated by density gradient centrifugation. ImmunoEM showed t...

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Huvudupphovsmän: Mullock, Barbara M., Bright, Nicholas A., Fearon, Clare W., Gray, Sally R., Luzio, J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1998
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140175/
https://ncbi.nlm.nih.gov/pubmed/9456319
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