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CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency

The establishment of HIV proviral latency requires the creation of repressive chromatin structures that impair the initiation of transcription and restrict RNAP II elongation. We have found that C-promoter binding factor-1 (CBF-1), a CSL (CBF-1, Su(H) and Lag-1)-type transcription factor and key eff...

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Detalhes bibliográficos
Main Authors: Tyagi, Mudit, Karn, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140115/
https://ncbi.nlm.nih.gov/pubmed/18007589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601928
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