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RKIP does not contribute to MAP kinase pathway silencing in the Merkel Cell Carcinoma cell line UISO

BACKGROUND: The Raf kinase inhibitor protein (RKIP) has been shown to block MAP kinase pathway as well as NFκB signalling. By means of immunohistochemistry, we previously demonstrated that the MAP kinase pathway is virtually inactive in Merkel cell carcinoma (MCC). Similarly to MCC in situ high RKIP...

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Main Authors: Houben, Roland, Ortmann, Sonja, Becker, Juergen C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140056/
https://ncbi.nlm.nih.gov/pubmed/17958888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-6-16
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